Microbiological therapy is a multicomponent treatment system aimed at regulating the immune system and increasing the body's defenses through live and inactivated bacteria and their components.
The main goals in conducting microbiological therapy:
immunomodulation of the body
immunomodulation of microflora
detoxification of organs and systems
regeneration of organs and systems
it is restoration of disrupted self-restoration and regulation mechanisms and homeostasis.
The surfaces of external contact (skin) and internal contact (mucous membranes of the oral cavity, gastrointestinal tract) of a healthy person are rich in microorganisms. There are approximately 10 14 microbial colonization on the surface of the entire digestive tract. Up to now, about 400 types of microorganisms living in the skin and mucous membranes have been identified. These microbial populations living in the skin and mucous membranes are in ecological balance with the host organism and play the role of symbionts and saprophytes. Of these microorganisms, lactobacilli and enterococci predominate in the small intestines, and anaerobic bacteria predominate in the large intestines.
The normal microflora of the intestines performs many important functions for the body:
They prevent pathogenic microorganisms (fungi, clostridia) from living by forming a microbiological barrier on the surface of the intestinal mucosa.
Normal microflora participate in the synthesis of many nutrients and vitamins (vit K, vit B12, fol.ac, nicotinamide)
They perform an immunoregulatory function
They participate in the development and differentiation of lymphoid organs
They have an activating effect on intestinal peristalsis
They participate in the regeneration and proliferation of the mucous membrane epithelium of the intestines
They accelerate local blood circulation in the intestinal mucosa.
The mechanisms underlying the immunomodulatory effect of microbiological therapy are related to the effect of microorganisms on the synthesis of immunoregulatory cytokines (GM-CSF, gamma-interferon) and inflammatory cytokines (Il 1b, Il 6). Thus, the drug Pro Symbioflor inhibits interleukin 1b and interleukin 6, stimulates the production of interleukin 2 and gamma-interferon, and as a result prevents inflammatory processes initiated by T lymphocytes and macrophages.
Due to the effect of Symbioflor 1 and Symbioflor 2 preparations, the synthesis of secretory immunoglobulin A increases, while the amount of circulating immunoglobulin G decreases. The lactic acid bacteria included in the composition of the SymbioLact preparation are important in stabilizing the environment in the gastrointestinal tract and protecting against pathogenic microflora.
Microbiological preparations with an original composition and mechanism of action are produced by the German company Symbio Pharm. Only healthy people and conditionally pathogenic strains whose virulence has been repeatedly tested in studies are used in the preparation of the medicines.
The stamps used in the preparation of the medicines are the products of colonies that have been reproduced from healthy people since 1950 and modern, very virulent, antibiotic-resistant stamps have not been formed.
For this reason, no side effects occur during the use of preparations and there is no possibility of infection with pathogenic microflora.
The effectiveness of microbiological therapy in the treatment of many diseases with an immune deficiency and allergic component has been proven. The effective effect of microbiological therapy has been proven in studies conducted in many European countries.
In a multicentric, retrospective, epidemiological cohort study involving 431 children at the German Biometric Institute (Hannover), the effectiveness of the Simbioflor 1 and Symbioflor 2 drugs in the complex treatment of neurodermatitis and in the complex treatment of atopic dermatitis in children at the Kyiv Medical University named after A.A. Bogomols was confirmed.
Diseases treated by microbiological therapy are:
allergic skin diseases (contact eczema, urticaria)
acute, chronic enterocolitis
irritable bowel syndrome
acne, furunculosis, etc
Microbiological therapy can be used as monotherapy or as part of any complex treatment. The use of microbiological therapy with antihomotoxic therapy is especially effective, as the synergistic effect of both therapies helps to achieve deeper and faster clinical results.